品牌	商品编码	商品名称	规格	单位	单价
HAOKEBIO	HKI0011A	细胞角蛋白8兔单克隆抗体	100ul	支	750

Applications

Tested Applications:

IHC, WB,ELISA

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Species Specificity:

human

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Positive WB detected in:

A549 cells

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Positive IHC detected in:

human stomach tissue, human stomach cancer tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

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Recommended dilution:

WB : 1:500-1:2000

IHC : 1:20-1:200

Product Information

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Source:

Mouse

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Purification method:

Protein A purification

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Isotype:

IgG3

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Immunogen Information

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Immunogen:

Peptide

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Full name:

keratin 8

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Calculated molecular weight:

54 kDa

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Observed molecular weight:

54 kDa

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Gene symbol

KRT8

---

Synonyms

CARD2, CK 8, CK8, CYK8, Cytokeratin 8, K2C8, K8, keratin 8, KO, KRT8, Type II keratin Kb8

Background

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT8 is often paired with keratin 18 in vivo.