CDX-2兔单克隆抗体

一抗 产品 抗体 2590
CDX-2兔单克隆抗体

CDX-2兔单克隆抗体

  • 价格¥1125
  • 规格100ul
  • 货号HKI0071A
  • 单位
  • 品牌HaoKebio

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产品参数
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品牌商品编码商品名称规格单位单价
HaoKebioHKI0071ACDX-2兔单克隆抗体100ul1125

Applications

Tested Applications:

WB,ELISA


Cited Applications:

IF, WB


Species Specificity:

human, mouse, rat, pig


Cited Species:

human, mouse, rat


Positive WB detected in:

COLO 320 cells, HT-29 cells, SW 1990 cells, pig colon tissue


Recommended dilution:

WB : 1:1000-1:6000

Product Information


Source:

Mouse


Purification method:

Protein A purification


Isotype:

IgG1


Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:

caudal type homeobox 2


Calculated molecular weight:

313 aa, 34 kDa


Observed molecular weight:

33-40 kDa

Gene symbol

CDX2


Synonyms

caudal type homeobox 2, Caudal type homeobox protein 2, CDX 3, CDX2, CDX-2, CDX3, Homeobox protein CDX 2

Background

CDX2, also named as Homeobox protein CDX-2, is a 313 amino acid protein, which contains one homeobox DNA-binding domain and belongs to the Caudal homeobox family. CDX2 localizes in the nucleus and is involved in the transcriptional regulation of multiple genes expression in the intestinal epithelium. The relative expression of CDX1 to CDX2 protein may be important in the anterior to posterior patterning of the intestinal epithelium and in defining patterns of proliferation and differentiation along the crypt-villus axis. Both Cdx1 and Cdx2 genes must be expressed to reduce tumorigenic potential, to increase sensitivity to apoptosis, and to reduce cell migration, suggesting that the two genes control the normal phenotype by independent pathways.

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