杭州浩克生物
甲状腺转录因子-1TTF-1兔单克隆抗体
305Tested Applications: IHC, WB,ELISA Cited Applications: WB Species Specificity: human, pig Cited Speci...
查看全文BCL2L1兔多克隆抗体
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| KAOKEBIO | HK210039L | BCL2L1兔多克隆抗体 | 200ul | 支 | 2800 |
Applications
Tested Applications:
FC, IF, IHC, IP, WB,ELISA
Cited Applications:
CoIP, IHC, WB
Species Specificity:
human, mouse
Cited Species:
human, mouse, rat
Positive WB detected in:
NIH/3T3 cells, RAW 264.7 cells
Positive IP detected in:
NIH/3T3 cells
Positive IHC detected in:
human testis tissue, human lung cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected in:
HepG2 cells
Positive FC detected in:
Jurkat cells
Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:500
IF : 1:50-1:500
Product Information
Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information
Full name:
BCL2-like 1
Calculated molecular weight:
26 kDa
Observed molecular weight:
30 kDa
Gene symbol
BCL2L1
Synonyms
Apoptosis regulator Bcl X, BCL2L1, Bcl-xL
Background
BCL2L1 is a member of the BCL-2 protein family. BCL2L1 is expressed as three isoforms, Bcl-X(L),Bcl-X(s) and Bcl-X(beta), and is located at the outer mitochondrial membrane. The Bcl-XL isoform is a 233 amino acid protein, acting as an apoptotic inhibitor. Bcl-XL can forms heterodimers with BAX, BAK or BCL2, and the heterodimerization with BAX does not seem to be required for anti-apoptotic activity. The Bcl-XS isoform is a shorter variant that is 178 amino acids in length and lacks a 63 amino acid region (amino acids 126-188), acting as an apoptotic activator. This antibody can recognize Bcl-XL, Bcl-XS and Bcl-X(Beta).
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