杭州浩克生物
ARL13B兔多克隆抗体
2品牌 商品编码 商品名称 规格 单位 单价 KAOKEBIO HK210015L ARL13B兔多克隆抗体 200ul 支 2800 Applications Tested Applications: IF, IHC, IP, WB,ELISA Cited ...
详情咨询BDNF兔多克隆抗体
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| KAOKEBIO | HK210043S | BDNF兔多克隆抗体 | 50ul | 支 | 1200 |
Applications
Tested Applications:
IF, IHC, WB,ELISA
Cited Applications:
IF, IHC, WB
Species Specificity:
Human, mouse, rat
Cited Species:
human, mouse, rat
Positive WB detected in:
C6 cells, SH-SY5Y cells, PC-12 cells
Positive IHC detected in:
human gliomas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected in:
PC-12 cells
Recommended dilution:
WB : 1:500-1:2000
IHC : 1:200-1:800
IF : 1:50-1:500
Product Information
Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information
Full name:
brain-derived neurotrophic factor
Calculated molecular weight:
247 aa, 28 kDa
Observed molecular weight:
28-30 kDa
Gene symbol
BDNF
Synonyms
Abrineurin, BDNF
Background
BDNF is a member of the family of neurotrophic factors. It was first explored and purified from pig brain in 1982, and other members of the neurotrophin family were successively discovered. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of BDNF is reduced in both Alzheimer’s and Huntington disease patients. It participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. It also plays a role in the regulation of stress response and in the biology of mood disorders. The BDNF gene is rather complex in its structure and it can express five different mRNA isoforms by alternative splicing, producing 28-37 kDa proteins.
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