MyelinBasicProtein兔单克隆抗体
3品牌 商品编码 商品名称 规格 单位 单价 HAOKEBIO HKI0731B MyelinBasicProtein兔单克隆抗体 1ml 支 11812.5 Applications Tested Applications...
详情咨询品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
---|---|---|---|---|---|
KAOKEBIO | HK210044L | Beclin 1兔多克隆抗体 | 200ul | 支 | 2800 |
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Beclin 1, also known as ATG6 or VPS30, interacts with various cofactors (e.g. Ambra1, Barkor (Atg14), Rubicon, or UVRAG) to regulate the lipid kinase Vps34 and promote the formation of the BECLIN1-Vps34-Vps15 complex, hence inducing autophagy. Its function (via the BH3 domain) is inhibited by Bcl-2 or Bcl-XL. Beclin 1 (BECN1) is a crucial molecule in the control of the autophagic activity, and its activity is regulated by multiple mechanisms, including the post-translational modification, protein-protein interaction, and subcellular localization. It plays a role in crosstalk between apoptosis and autophagy. It has been reported that Beclin 1 can be cleaved into fragments of 50, 37 and 35 kDa during apoptosis. It is involved in many disorders, including neurodegeneration and cancer (tumorigenesis). Beclin 1 is a mammalian tumor suppressor, and its gene is monoallelically deleted in 75% of ovarian, 50% of breast, and 40% of prostate cancers. Decreased expression of Beclin 1 has also been observed in human brain and lung tumors. The level of Beclin 1 was decreased in the affected brain regions of patients with Alzheimer’s disease early in the disease process. Recent studies have also shown that gain and loss of Beclin 1 function affects the death of heart cells.
品牌 商品编码 商品名称 规格 单位 单价 HAOKEBIO HKI0731B MyelinBasicProtein兔单克隆抗体 1ml 支 11812.5 Applications Tested Applications...
详情咨询品牌 商品编码 商品名称 规格 单位 单价 HAOKEBIO HK510145L PCNA鼠单克隆抗体 200ul 支 2800 Applications Tested Applications: FC, IF, IHC, IP, WB, ELISA Cited...
详情咨询Product Information Description GSTA1 rabbit polyclonal Protein full name Glutathione S-transferase A1 Synonyms Cell division protein kinase 9, Cdk9, C 2k, CDC2L4, C...
详情咨询品牌 商品编码 商品名称 规格 单位 单价 HAOKEBIO HKI0291B GranzymeB兔单克隆抗体 1ml 支 10500 Applications Tested Applications: FC, IF, IHC, WB,ELISA ...
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