品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HK510008L	ARL13B鼠单克隆抗体	200ul	支	2800

Applications

Tested Applications:

IF, WB,ELISA

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Cited Applications:

IF

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Species Specificity:

Canine, Human, mouse, pig

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Cited Species:

human, mouse, rat

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Positive WB detected in:

HepG2 cells, HEK-293 cells, NCCIT cell

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Positive IF detected in:

MDCK cells

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Recommended dilution:

WB : 1:1000-1:6000

IF : 1:50-1:500

Product Information

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Source:

Mouse

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Purification method:

Protein A purification

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Isotype:

IgG2a

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Immunogen Information

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Full name:

ADP-ribosylation factor-like 13B

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Calculated molecular weight:

48 kDa

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Observed molecular weight:

60 kDa

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Gene symbol

ARL13B

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Synonyms

ARL13B, ARL2 like protein 1, ARL2L1, DKFZp686E2075, DKFZp686L2472, DKFZp686M2074, DKFZp761H079, JBTS8

Background

ARL13B, also named as ARL2L1, is a small ciliary G protein of the Ras superfamily. Localized in the cilia, it is required for cilium biogenesis and sonic hedgehog signaling. Defects in ARL13B are the cause of Joubert syndrome (JS) which is an autosomal recessive disorder characterized by a distinctive cerebellar malformation (PMID: 19906870). Arl13b is predicted to be a 48 kDa protein, and the 60 kDa band is likely to represent a modified form of Arl13b. ARL13B can be used to mark the cilia (PMID:22072986).