杭州浩克生物
SOX-11兔单克隆抗体
180Tested Applications: WB, ELISA Cited Applications: WB Species Specificity: human Cited Species: human Pos...
查看全文CD31兔多克隆抗体
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| KAOKEBIO | HK210080L | CD31兔多克隆抗体 | 200ul | 支 | 2800 |
Applications
Tested Applications:
FC, IF, IHC, IP, WB,ELISA
Cited Applications:
IF, IHC, IP, WB
Species Specificity:
human
Cited Species:
human, monkey
Positive WB detected in:
Jurkat cells
Positive IP detected in:
Jurkat cells
Positive IHC detected in:
human hepatocirrhosis tissue, human tonsillitis tissue, human liver cancer tissue, human gliomas tissue, human renal cell carcinoma tissue, human kidney tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected in:
human tonsillitis tissue
Positive FC detected in:
HUVEC cells
Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:800-1:4000
IF : 1:50-1:500
Product Information
Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information
Full name:
platelet/endothelial cell adhesion molecule
Calculated molecular weight:
83 kDa
Observed molecular weight:
130 kDa
Gene symbol
PECAM1
Synonyms
CD31, EndoCAM, GPIIA, PECA1, PECAM 1, PECAM1, VEC marker
Background
Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).
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