CDK3兔多克隆抗体

品牌 商品编码 商品名称 规格 单位 单价
KAOKEBIO HK210090S CDK3兔多克隆抗体 50ul 1200

Applications

Tested Applications:
FC, IHC, WB,ELISA

Cited Applications:
WB
Species Specificity:
human, mouse

Cited Species:
mouse

Positive WB detected in:
mouse brain tissue, MCF-7 cells, Jurkat cells, rat brain tissue

Positive IHC detected in:
human breast cancer tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Positive FC detected in:
HeLa cells

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:100-1:400

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
0.1M NaHCO3, 0.1M glycine, 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
cyclin-dependent kinase 3

Calculated molecular weight:
35 kDa

Observed molecular weight:
40-45 kDa

Gene symbol
CDK3

Synonyms
CDK3, Cell division protein kinase 3, cyclin dependent kinase 3

Background

CDK3 belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily. It is probably involved in the control of the cell cycle. CDK3 interacts with a yet unknown type of cyclin. It can phosphorylate histone H1. Endogenous Cyclin C/Cdk3 complexes are critical to promote exit from quiescence in an Rb-dependent manner. Cyclin C/Cdk3 complexes is a key regulators of cell cycle reentry in human cells. (PMID: 15130482 )The antibody is specific to CDK3.

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