Caspase 4兔多克隆抗体

品牌 商品编码 商品名称 规格 单位 单价
KAOKEBIO HK210067L Caspase 4兔多克隆抗体 200ul 2800

Applications

Tested Applications:
IF, IHC, WB, ELISA

Cited Applications:
WB

Species Specificity:
human

Cited Species:
human

Positive WB detected in:
SGC-7901 cells

Positive IHC detected in:
human pancreas cancer tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
caspase 4, apoptosis-related cysteine peptidase

Calculated molecular weight:
377 aa, 43 kDa

Observed molecular weight:
43-48 kDa

Gene symbol
CASP4

Synonyms
CASP 4, CASP4, Caspase 4, Caspase 4/p20/p10, Caspase4, ICE(rel) II, ICE(rel)II, ICEREL II, ICH 2, ICH2, Mih1/TX, Protease ICH 2, Protease TX, TX

Background

Caspase 4 (CASP4), is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.Caspase 4 is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. Overexpression of caspase 4 will induce cell apoptosis.

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