Caspase 6兔多克隆抗体
180Applications Product Information Immunogen Information Background
查看全文品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
---|---|---|---|---|---|
HAOKEBIO | HK210063L | Caspase 1兔多克隆抗体 | 200ul | 支 | 2800 |
HAOKEBIO | HK210063S | Caspase 1兔多克隆抗体 | 50ul | 支 | 1200 |
human spleen tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta (IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products(PMID:21804020). It has 5 isoforms produced by alternative splicing. 22915-1-AP can recognize all the five isoforms of caspase 1. It also can recognize p45 procaspase and the mature fragments p10 and p20.
Tested Applications: IF, IHC, WB,ELISA Species Specificity: human, mouse Positive WB detected in: Raji...
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