品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HK510115M	IL-4鼠单克隆抗体	100ul	支	1960

Applications

Tested Applications:

IF, IHC, WB, ELISA

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Cited Applications:

ELISA, IF, IHC, WB

Species Specificity:

human, pig

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Cited Species:

human, rat

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Positive WB detected in:

Jurkat cells

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Positive IHC detected in:

human tonsillitis tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

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Positive IF detected in:

human breast cancer tissue

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Recommended dilution:

WB : 1:500-1:2000

IHC : 1:20-1:200

IF : 1:200-1:800

Product Information

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Source:

Mouse

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Purification method:

Protein G purification

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Isotype:

IgG2a

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Immunogen Information

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Full name:

interleukin 4

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Calculated molecular weight:

153 aa, 17 kDa

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Observed molecular weight:

18 kDa

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Gene symbol

IL4

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Synonyms

B cell stimulatory factor 1, Binetrakin, BSF 1, BSF1, IL 4, IL4, IL-4, interleukin 4, PS1TP5BP1

Background

IL4 is a cytokine produced by CD4+ T cells in response to helminthes and other extracellular parasites. It promotes the proliferation and differentiation of antigen presenting cells. IL4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival.