MyelinBasicProtein兔单克隆抗体
170Applications Applications Product Information Immunogen Information Background Protocols PRODUCT SPECIFIC PROTOCOLS Product Information Imm...
查看全文品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
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KAOKEBIO | HK210122L | Cyclin D3兔多克隆抗体 | 200ul | 支 | 2800 |
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
cyclin D3 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.
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