杭州浩克生物
ALDH1A1鼠单克隆抗体
2品牌 商品编码 商品名称 规格 单位 单价 HAOKEBIO HK510005M ALDH1A1鼠单克隆抗体 100ul 支 1960 Applications Tested Applications: IF, IHC, WB,ELISA Cited Appli...
详情咨询Cyclin B2兔多克隆抗体
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| KAOKEBIO | HK210119S | Cyclin B2兔多克隆抗体 | 50ul | 支 | 1200 |
Applications
Tested Applications:
IHC, IP, WB,ELISA
Cited Applications:
IHC, WB
Species Specificity:
human, mouse, rat
Cited Species:
human
Positive WB detected in:
HeLa cells, DU 145 cells, rat testis tissue, A431 cells, K-562 cells
Positive IP detected in:
A431 cells
Positive IHC detected in:
human cervical cancer tissue, human testis tissue, human colon cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
Product Information
Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information
Full name:
cyclin B2
Calculated molecular weight:
398 aa, 45 kDa
Observed molecular weight:
51 kDa
Gene symbol
CCNB2
Synonyms
CCNB2, cyclin B2, G2/mitotic specific cyclin B2, HsT17299
Background
Cyclin B2 (CCNB2) is a member of cyclin family proteins, which regulate the activities of cyclin dependent kinases (CDKs) and different cyclins function spatially and temporally in specific phases of the cell cycle. Cyclin B2 serves a key role in progression of G2/M transition. Cyclin B2 has been found to be up-regulated in a variety of human cancers, such as adrenocortical carcinoma, breast carcinoma, colorectal adenocarcinoma, pituitary adenoma and gastric cancer. The aberrant expression of Cyclin B2 deregulates spindle checkpoints in the cell cycle and results in chromosomal instability (CIN), one of the signature phenotypes of most cancers. Moreover, serum circulating Cyclin B2 mRNA expression has been found increased in cancer patients and associated with cancer stage and metastasis status.
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