CPT1A兔多克隆抗体

品牌 商品编码 商品名称 规格 单位 单价
KAOKEBIO HK210111S CPT1A兔多克隆抗体 50ul 1200

Applications

Tested Applications:
FC, IF, IHC, IP, WB, ELISA

Cited Applications:
FC, IF, IHC, IP, WB

Species Specificity:
human, mouse, rat

Cited Species:
bovine, human, mouse, rat, zebrafish

Positive WB detected in:
mouse liver tissue, A549 cells, HepG2 cells, MCF-7 cells, U-251 cells, mouse brain, rat brain

Positive IP detected in:
HepG2 cells

Positive IHC detected in:
human liver cancer tissue, mouse brain tissue, human kidney tissue, human colon tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Positive IF detected in:
HepG2 cells, Hela cells

Positive FC detected in:
HeLa cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:500
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
carnitine palmitoyltransferase 1A (liver)

Calculated molecular weight:
88 kDa

Observed molecular weight:
86 kDa

Gene symbol
CPT1A

Synonyms
CPT I, CPT1, CPT1 L, CPT1A, CPTI L, L CPT1

Background

CPT1A, also named as CPT1, CPT1-L and L-CPTI, belongs to the carnitine/choline acetyltransferase family. It is Localized Chromosome 11q13.1-2. Carnitine palmitoyltransferase (CPT) deficiencies are common disorders of mitochondrial fatty acid oxidation. The CPT system is made up of two separate proteins located in the outer (CPT1) and inner (CPT2) mitochondrial membranes. CPT1A is an active forms of related liver-type carnitine palmitoyltransferase I. (PMID: 11001805). CPT1A deficiency presents as recurrent attacks of fasting hypoketotic hypoglycemia. (PMID: 15363638). This antibody can bind the close sequences genes.

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