CP110兔多克隆抗体

品牌 商品编码 商品名称 规格 单位 单价
KAOKEBIO HK210110S CP110兔多克隆抗体 50ul 1200

Applications

Tested Applications:
FC, IHC, IP, WB,ELISA

Cited Applications:
IF, IHC, IP, WB
Species Specificity:
human, mouse, rat, Canine

Cited Species:
canine, Drosophila, human, mouse, rat, Xenopus, zebrafish

Positive WB detected in:
HEK-293T cells, HeLa cells, Jurkat cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human testis tissue, human prostate cancer tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Positive FC detected in:
HeLa cells

Recommended dilution:
WB : 1:1000-1:6000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
CP110 protein

Calculated molecular weight:
991 aa, 111 kDa

Observed molecular weight:
113 kDa

Gene symbol
CP110

Synonyms
Centrosomal protein of 110 kDa, CP110, CP110 protein, KIAA0419

Background

CP110, also named as CCP110 and KIAA0419, is an 110kDa protein. This gene is different to the gene CEP110 (geneID:11064; CNTRL). CP110 is a centriolar protein that positively regulates centrioleduplication while restricting centriole elongation and ciliogenesis. And it acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation.

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