ATG13兔多克隆抗体

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品牌 商品编码 商品名称 规格 单位 单价
KAOKEBIO HK210021S ATG13兔多克隆抗体 50ul 1200

Applications

Tested Applications:
IF, IHC, IP, WB,ELISA
Cited Applications:
WB

Species Specificity:
human, mouse, rat

Cited Species:
human, mouse, rat

Positive WB detected in:
SH-SY5Y cells, mouse thymus tissue, human brain tissue, mouse cerebellum tissue, mouse testis tissue, BGC-823 cells

Positive IP detected in:
SH-SY5Y cells

Positive IHC detected in:
mouse heart tissue, mouse brain tissue, human brain tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Positive IF detected in:
SH-SY5Y cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
KIAA0652

Calculated molecular weight:
57 kDa

Observed molecular weight:
57-63 kDa
Gene symbol
KIAA0652

Synonyms
ATG13, Autophagy related protein 13, KIAA0652

Background

ATG13 is one component protein of the ULK1 complex which is required for autophagosome formation and mitophagy. ATG13 has two nutrient regulatory phosphorylation sites and the phosphorylation status of ATG13 affect regulation of autophagy by modulating enzyme activity and cellular localization of ULK1. Besides, it has been reported the nonautophagic function of ATG13 on cardiac development for ATG13-deficient embryos show myocardial growth defects.(PMID:27387056, 26801615, 26644405)

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