| 产品名称 | TROP-2 Recombinant antibody |
|---|---|
| 产品编号 | HB50320 |
| 发货周期 | 现货 |
| Uniprot ID | P09758 |
| Host Species | Rabbit |
| Reactivity | human |
| Tested Applications | IHC |
| Application | IHC :1:100 -1:200,IHC-Polymer:1:400-1:800,TSA:1:1000-1:2000 |
| Background | Trophoblast cell surface antigen 2 (TROP2), also named as TACSTD2, is a transmembrane glycoprotein. TROP2 plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. TROP2 is overexpressed in most carcinomas and is involved in cancer proliferation, migration, invasion, and metastasis. Congenital mutations of TROP2 cause a rare autosomal recessive disease which may lead to blindness-the gelatinous drop-like corneal disease (PMID: 35688908). |
| Alternative Names | TACSTD2, Cell surface glycoprotein Trop-2, EGP 1, GA733, GA733 1 |
| Immunogen | Synthetic Peptide |
| Calculated MW | 36 kDa |
| Subcellular Localization | Membrane |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Purification | Protein A affinity purified |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%. |
| Formulation | Liquid |
| Storage | Store at -20°C |
| 保质期 | 12 months |