| 产品名称 | Granzyme B Recombinant antibody, Cytotoxic granule marker |
|---|---|
| 产品编号 | HB50307 |
| 发货周期 | 现货 |
| Uniprot ID | P04187 |
| Host Species | Rabbit |
| Reactivity | human, mouse, rat |
| Tested Applications | IHC |
| Application | IHC :1:100 -1:200 |
| Background | This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016] |
| Alternative Names | GZMB, CSP B, CGL1, CGL 1, CCPI |
| Immunogen | Recombinant protein of human Granzyme B |
| Subcellular Localization | Secretory vesicle |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Purification | Affinity Purification |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%. |
| Formulation | Liquid |
| Storage | Store at -20°C |
| 保质期 | 12 months |
