| 产品名称 | gamma H2A.X (phospho S139) Recombinant antibody |
|---|---|
| 产品编号 | HB50319 |
| 发货周期 | 现货 |
| Uniprot ID | P16104 |
| Host Species | Rabbit |
| Reactivity | human, mouse, rat |
| Tested Applications | IHC |
| Application | IHC :1:100 -1:200，IHC-Polymer:1:400-1:800，TSA:1:1000-1:2000 |
| Background | Gamma H2A.X (γH2A.X) is a phosphorylated form of the H2A histone family member X (H2AX), which plays a crucial role in the cellular response to DNA damage. When double-strand breaks occur in DNA, H2AX is rapidly phosphorylated at serine 139 to form γH2A.X. This modification serves as a marker for DNA damage and is essential for recruiting DNA repair proteins to the site of damage. Researchers use γH2A.X as a sensitive indicator of DNA double-strand breaks in studies of genotoxic stress, cancer and other conditions involving DNA damage and repair. |
| Alternative Names | p-H2A.X (S139) , H2A.X pS139, H2AX S139p |
| Immunogen | Synthetic Peptide |
| Calculated MW | 16 kDa |
| Subcellular Localization | Nucleus |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Purification | Protein A affinity purified |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%. |
| Formulation | Liquid |
| Storage | Store at -20°C |
| 保质期 | 12 months |
