| 产品名称 | Caspase 3/P17/P19 Recombinant antibody |
|---|---|
| 产品编号 | HB50312 |
| 发货周期 | 现货 |
| Uniprot ID | P42574 |
| Host Species | Rabbit |
| Reactivity | human, mouse, rat |
| Tested Applications | IHC |
| Application | IHC :1:100 -1:200 |
| Background | The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017] |
| Alternative Names | CASP3, Caspase3, CASP 3, CASP-3, Caspase 3 |
| Immunogen | Recombinant protein of human Caspase-3 |
| Subcellular Localization | Cytoplasm |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Purification | Affinity Purification |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%. |
| Formulation | Liquid |
| Storage | Store at -20°C |
| 保质期 | 12 months |
