| 产品名称 | Acetyl-Histone H4 (Lys12) Recombinant antibody |
|---|---|
| 产品编号 | HB50264 |
| 发货周期 | 现货 |
| Uniprot ID | P62805 |
| Host Species | Rabbit |
| Reactivity | human, mouse, rat |
| Tested Applications | IHC |
| Application | IHC :1:100 -1:200 |
| Background | Histone H4 is a 103 amino acid protein, which belongs to the histone H4 family. Histone H4 localizes in the nucleus and is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Acetylation of histone H4 is necessary for chromatin decompaction during DNA replication. |
| Alternative Names | Ac Histone H4, Ac Histone H4 (Lys12), Ac Histone H4 Lys12, Ac Histone H4-Lys12, Acetyl Histone |
| Immunogen | Peptide |
| Subcellular Localization | Nucleus |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Purification | Protein A purfication |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%. |
| Formulation | Liquid |
| Storage | Store at -20°C |
| 保质期 | 12 months |
