CD13鼠单克隆抗体

一抗 产品 抗体 3280
CD13鼠单克隆抗体

CD13鼠单克隆抗体

  • 价格¥2800
  • 规格200ul
  • 货号HK510044L
  • 单位
  • 品牌HaoKebio

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HAOKEBIOHK510044LCD13鼠单克隆抗体200ul2800

Applications

Tested Applications:

FC, IF, IHC, WB,ELISA


Cited Applications:

IF, IHC, WB


Species Specificity:

human


Cited Species:

human


Positive WB detected in:

U-937 cells


Positive IHC detected in:

human tonsillitis tissue, human kidney tissue, mouse kidney tissue, rat kidney tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Positive IF detected in:

human kidney tissue


Positive FC detected in:

U-937 cells


Recommended dilution:

WB : 1:3000-1:8000

IHC : 1:5000-1:20000

IF : 1:50-1:500

Product Information


Source:

Mouse


Purification method:

Protein A purification


Isotype:

IgG2a


Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:

alanyl (membrane) aminopeptidase


Calculated molecular weight:

110 kDa


Observed molecular weight:

150 kDa


Gene symbol

ANPEP


Synonyms

Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, ANPEP, AP M, AP N, APN, CD13, gp150, hAPN, LAP1, Microsomal aminopeptidase, p150, PEPN

Background

CD13, also named as APN, ANPEP(aminopeptidase N) or PEPN, is belongs to the peptidase M-1 family. CD13 is a heavily glycosylated, ~150-240 kDa, type-II membrane, expressed by most cells of myeloid origin including monocytes, macrophages, granulocytes, and their hematopoietic precursors. It is also abundantly expressed in the brush border of epithelial cells from renal proximal tubules and small intestine, in prostatic epithelial cells, in bile duct canaliculi, in mast cells, and, in some cases, in fibroblasts and smooth muscle cells. CD13 is a multifunctional protein and plays varying roles in cell migration, cell proliferation, cell differentiation and so on. CD13 participates in angiogenesis generating and modulating angiogenic signals, and can be a marker of angiogenic vessels. CD13 is also a pan-myeloid marker, present on mature granulocytes and monocytes. (PMID: 8805662, 10098327, 18603472, 18097955, 17897790, 17888402, 21339174)

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