CD31兔单克隆抗体

一抗 产品 抗体 3620
CD31兔单克隆抗体

CD31兔单克隆抗体

  • 价格¥1313
  • 规格100ul
  • 货号HKI0351A
  • 单位
  • 品牌HaoKebio

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HaoKebioHKI0351ACD31兔单克隆抗体100ul1313

Applications

Tested Applications:

IF, IHC, WB, ELISA


Cited Applications:

IF, IHC, WB

Species Specificity:

Human


Cited Species:

human


Positive WB detected in:

human peripheral blood platelets, Jurkat cells, THP-1 cells


Positive IHC detected in:

human liver cancer tissue, human breast cancer tissue, human tonsillitis tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Positive IF detected in:

human liver cancer tissue


Recommended dilution:

WB : 1:5000-1:50000

IHC : 1:5000-1:20000

IF : 1:200-1:800

Product Information


Source:

Mouse


Purification method:

Protein A purification


Isotype:

IgG1


Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Aliquoting is unnecessary for -20oC storage.


Full name:

platelet/endothelial cell adhesion molecule


Calculated molecular weight:

83 kDa


Observed molecular weight:

120-130 kDa


Gene symbol

PECAM1


Synonyms

CD31, EndoCAM, FLJ58394, GPIIA, PECA1, PECAM 1, PECAM1, VEC marker

Background

Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489)

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