CD23鼠单克隆抗体
198Tested Applications: IF, IHC, WB,ELISA Species Specificity: human, mouse Cited Species: human Positive...
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---|---|---|---|---|---|
KAOKEBIO | HK210105L | c-Met (Cytoplasmic)兔多克隆抗体 | 200ul | 支 | 2800 |
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
c-Met (also named as MET or HGFR) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to HGF ligand. c-Met regulates many physiological processes including proliferation, scattering, morphogenesis and survival. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Overexpression and/or mutation of c-Met has been reported in various human malignancies, including lung cancer, breast cancer, head and neck cancer, gastric cancer, colorectal cancer, bladder cancer, uterine cervix carcinoma, and esophageal carcinoma, c-Met could serve as an important therapeutic target (PMID: 26036285). The c-met receptor is a 190-kD glycoprotein consisting of a 145-kD membrane-spanning beta chain and a 50-kD alpha chain (PMID: 7806559). In Western blot, this antibody produces bands of unknown identity at 55 and 100 kDa.
Tested Applications: IF, IHC, WB,ELISA Species Specificity: human, mouse Cited Species: human Positive...
查看全文Tested Applications: FC, IF, IHC, WB,ELISA Cited Applications: IF, IHC, WB Species Specificity: hu...
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