品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKI0721A	CD38兔单克隆抗体	100ul	支	1050

Applications

Tested Applications:

FC, IF, WB,ELISA

Cited Applications:

IHC, WB

Species Specificity:

human, mouse

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Cited Species:

human, mouse

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Positive WB detected in:

Jurkat cells, Raji cells

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Positive IF detected in:

NIH/3T3 cells

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Positive FC detected in:

Daudi cells

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Recommended dilution:

WB : 1:500-1:2000

IF : 1:10-1:100

Product Information

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Source:

Mouse

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Purification method:

Protein G purification

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Isotype:

IgG1

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Immunogen Information

Full name:

CD38 molecule

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Calculated molecular weight:

300 aa, 34 kDa

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Observed molecular weight:

45 kDa

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Gene symbol

CD38

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Synonyms

ADP ribosyl cyclase 1, cADPr hydrolase 1, CD38, CD38 molecule, Cyclic ADP ribose hydrolase 1, T10

Background

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).

Protocols

PRODUCT