杭州浩克生物Product Information
| Description | GSTA1 rabbit polyclonal |
| Protein full name | Glutathione S-transferase A1 |
| Synonyms | Cell division protein kinase 9, Cdk9, C 2k, CDC2L4, CTK1, PITALRE, TAK |
| Immunogen | 13-hydroperoxyoctadecadienoate peroxidase, Androst-5-ene-3, 17-dione isomerase, GST class-alpha member 1, Gsta1, Gsta, Gstya, Glutathione S-transferase Ya, Glutathione S-transferase Ya1, Glutathione S-transferase A1, N-terminally processed |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 26 kDa |
| Observed MW. | 26 kDa |
| Uniprot ID | P08263, P13745, P00502 |
Applications
| Applications | WB |
| Species | Mouse, Rat |
| Dilution | 1: 500-1: 1000 |
| Positive Tissue | liver, kidney |
Background
This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. Studies have shown that overexpression of GSTA1 can promote the growth of lung cancer cells, so the expression level of GSTA1 can be used to predict the degree of malignancy of lung cancer tissues. To some extent, GSTA1 is regarded as a potential lung cancer candidate targets.
Images
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Western blot analysis of GSTA1 (GB111400) at dilution of 1: 1000 Lane 1: Mouse liver tissue lysate Lane 2: Mouse kidney tissue lysate Lane 3: Rat liver tissue lysate Lane 4: Rat kidney tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
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