Myogenin兔单克隆抗体

Myogenin兔单克隆抗体

  • 价格¥600
  • 规格100ul
  • 货号HKZ150133
  • 单位
  • 品牌HaoKebio

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HaoKebioHKZ150133Myogenin兔单克隆抗体100ul600
Myogenin
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog#  HKZ150133 Clone#  BP6137
Predicted Molecular Wt:
32kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P15173
Background:
Myogenin belongs to a family of regulatory proteins essential for muscle development.
Myogenin is expressed on cells of skeletal muscle origin, and appears to be inversely related to the degree of cellular differentiation.
The antibody is a useful aid for classification of rhabdomyosarcomas and Wilms’ tumors. No reactivity with Ewing’s  sarcoma/peripheral primitive neuroectodermal tumor, neuroblastoma, or adult skeletal muscle has been observed.
Subcellular location:
Nucleus
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide corresponding to residues within aa100 to aa200 of Myogenin was used as an
immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Background References:
1. Combes AN  etal. Genome Med 11:3 (2019).
2.  McClure MJ  et al. Am J Physiol Cell Physiol 316:C876- C887 (2019).
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded  sections) analysis of embryonal
rhabdomyosarcoma
(ERMS) labelling Myogenin with BP6137. Heat
mediated antigen retrieval was performed using
Tris/EDTA buffer pH 9.0.

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