ER兔多克隆抗体

一抗 3920
品牌 商品编码 商品名称 规格 单位 单价
HAOKEBIO HK210143M ER兔多克隆抗体 100ul 1960

Applications

Tested Applications:
IHC, WB,ELISA

Cited Applications:
IF, WB
Species Specificity:
human, mouse, rat

Cited Species:
bovine, human, mouse, rat

Positive WB detected in:
HeLa cells, MCF-7 cells, mouse testis tissue, NIH/3T3 cells, rat testis tissue

Positive IHC detected in:

human cervical cancer tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Recommended dilution:
WB : 1:500-1:2000
IHC : 1:400-1:1600

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
estrogen receptor 1

Calculated molecular weight:
595 aa, 66 kDa

Observed molecular weight:
65-70 kDa

Gene symbol
ESR1

Synonyms
ER, ER alpha, Era, ERα, ESR, ESR1, ESRA, Estradiol receptor, Estrogen receptor, estrogen receptor 1, NR3A1

Background

The estrogen receptor (ESR, ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. ESR1, also known as ESR or NR3A1, belongs to the nuclear hormone receptor family and NR3 subfamily. It is a nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. ESR1 can activate the transcriptional activity of TFF1.[PMID: 11731608,10970861]

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