Caspase 2兔多克隆抗体

一抗 3260
品牌 商品编码 商品名称 规格 单位 单价
KAOKEBIO HK210065M Caspase 2兔多克隆抗体 100ul 1960

Applications

Tested Applications:
IHC, IP, WB,ELISA

Cited Applications:
ELISA, IF, RIP, WB
S


Species Specificity:
human, mouse, rat

Cited Species:
human, mouse, rabbit

Positive WB detected in:
Staurosporine treated Jurkat cells, HEK-293 cells, HeLa cells, HL-60 cells, Jurkat cells, mouse kidney tissue, mouse liver tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human kidney tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:1000-1:4000 for WB
IHC : 1:100-1:400

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
caspase 2, apoptosis-related cysteine peptidase

Calculated molecular weight:
452 aa, 51 kDa

Observed molecular weight:
51 kDa, 32 kDa, 18 kDa

Gene ID (NCBI):

Gene symbol
CASP2

Synonyms
CASP 2, CASP2, Caspase 2, Caspase 2/p18, Caspase2, ICH 1L, ICH 1L/1S, ICH1, NEDD 2, NEDD2, Protease ICH 1

Background

CASP2(Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution(PMID:15865942).

WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:1000-1:4000 for WB
IHC : 1:100-1:400
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