AMBRA1兔多克隆抗体

品牌 商品编码 商品名称 规格 单位 单价
KAOKEBIO HK210008L AMBRA1兔多克隆抗体 200ul 2800

Applications

Tested Applications:
IF, IHC, WB,ELISA
Cited Applications:
IHC, WB

Species Specificity:
human, mouse, rat

Cited Species:
human

Positive WB detected in:
MCF-7 cells, human brain tissue, HT-1080 cells, HepG2 cells, mouse brain tissue

Positive IHC detected in:
human liver cancer tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:500
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
autophagy/beclin-1 regulator 1

Calculated molecular weight:
1208 aa, 133 kDa

Observed molecular weight:
130-135 kDa

Gene symbol
AMBRA1

Synonyms
AMBRA1, autophagy/beclin 1 regulator 1, KIAA1736, WDR94

Background

AMBRA1 (Activating molecule in BECN1-regulated autophagy protein 1), also known as WDR94 or KIAA1736, is a 1,298 amino acid protein that contains three WD repeats. AMBRA1 regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation. This antibody works well in WB, IHC and IF application.

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