杭州浩克生物
Caspase 3兔多克隆抗体
10品牌 商品编码 商品名称 规格 单位 单价 KAOKEBIO HK210066L Caspase 3兔多克隆抗体 200ul 支 2800 Applications ested Applications: FC, IF, IHC, IP, WB,ELISA Cite...
查看全文AI兔多克隆抗体
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| KAOKEBIO | HK210005M | AI兔多克隆抗体 | 100ul | 支 | 1960 |
| KAOKEBIO | HK210005L | AI兔多克隆抗体 | 200ul | 支 | 2800 |
Applications
Tested Applications:
IF, IHC, IP, WB,ELISA
Cited Applications:
IF, IHC, WB
Species Specificity:
human, mouse, rat
Cited Species:
human, mouse, rat, sheep
Positive WB detected in:
HeLa cells, Jurkat cells, A549 cells, rat kidney tissue, NIH/3T3 cells
Positive IP detected in:
HeLa cells
Positive IHC detected in:
human kidney tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected in:
HepG2 cells
Recommended dilution:
WB : 1:1000-1:8000
IP : 0.5-4.0 ug for IP and 1:1000-1:4000 for WB
IHC : 1:100-1:400
IF : 1:10-1:100
Product Information
Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information
Full name:
apoptosis-inducing factor, mitochondrion-associated, 1
Calculated molecular weight:
609 aa, 66 kDa
Observed molecular weight:
67 kDa, 57 kDa
Gene symbol
AIFM1
Synonyms
AIF, AIFM1, PDCD8
Background
Apoptosis-inducing factor (AIF) is one of the mitochondrial proteins to be released into the cytosol during apoptosis, and it is discovered as the first protein that regulates caspase-independent apoptosis(PMID:20494118). AIF is encoded as a 67 kDa protein that contains a mitochondrial localization signal (MLS) in the N-terminus.It is cleaved from the 62 kDa to the 57 kDa form following ischemic injury and translocated from the mitochondria to the nucleus in a calpain-dependent manner(PMID:19332058).
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