杭州浩克生物
CEA兔单克隆抗体
53品牌 商品编码 商品名称 规格 单位 单价 HAOKEBIO HKI0601A CEA兔单克隆抗体 100ul 支 1088 Applications Tested Applications: IHC,ELISA Cited Applications: chI...
查看全文ABL2兔多克隆抗体
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| KAOKEBIO | HK210001L | ABL2兔多克隆抗体 | 200ul | 支 | 2800 |
| KAOKEBIO | HK210001M | ABL2兔多克隆抗体 | 100ul | 支 | 1960 |
Applications
Tested Applications:
IHC, IP, WB,ELISA
Cited Applications:
WB
Species Specificity:
human, mouse, rat
Cited Species:
human, mouse
Positive WB detected in:
mouse brain tissue
Positive IP detected in:
HeLa cells
Positive IHC detected in:
human liver cancer tissue, human gliomas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Recommended dilution:
Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information
Full name:
v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)
Calculated molecular weight:
1167 aa, 127 kDa
Observed molecular weight:
128-140 kDa
Gene symbol
ABL2
Synonyms
Abelson related gene protein, ABL2, ABLL, ARG, Tyrosine protein kinase ABL2, Tyrosine protein kinase ARG
Background
ABL2(Abelson tyrosine-protein kinase 2) is also named as ABLL, ARG and belongs to the protein kinase superfamily. It is a membrane-anchored nonreceptor tyrosine kinase that is a novel mediator of SEMA3F-induced RhoA inactivation and collapsing activity and it has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. ABL2 can be polyubiquitinated and the polyubiquitination of ABL2 leads to degradation. This protein has 9 isoforms produced by alternative splicing with the molecular weight from 114 kDa to 128 kDa. The antibody is specific to the others except the 60 kDa isoform of ABL2.
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
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