Tested Applications: FC, IF, IHC, WB,ELISA Cited Applications: IF, IHC, WB Species Specificity: hu...查看全文
chIP, IHC, WB
Positive IHC detected in:
human colon cancer tissue, human appendicitis tissue, human stomach cancer tissue, human lung cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
IHC : 1:200-1:800
Antigen affinity purification
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
carcinoembryonic antigen-related cell adhesion molecule 5
Calculated molecular weight:
Observed molecular weight:
Carcinoembryonic antigen, CD66e, CEA, CEACAM5, Meconium antigen 100
Carcinoembryonic antigen (CEA), also known as CEACAM5 or CD66e, is a cell surface glycoprotein belonging to the immunoglobulin superfamily, mainly serving as a cell adhesion molecule mediating intercellular contact by both homophilic and heterophilic binding (PMID: 21731662). CEA inhibits anoikis and plays a role in tumorigenesis and metastasis. CEA has been found to be overexpressed in a wide variety of human cancers, including colon, breast, and lung (PMID: 17167768). CEA is a tumor marker and is routinely exploited for diagnosis.