甲状腺转录因子-1TTF-1兔单克隆抗体

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甲状腺转录因子-1TTF-1兔单克隆抗体

甲状腺转录因子-1TTF-1兔单克隆抗体

  • 价格¥1650
  • 规格100ul
  • 货号HKI0621A
  • 单位
  • 品牌HaoKebio

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HaoKebioHKI0621A甲状腺转录因子-1TTF-1兔单克隆抗体100ul1650

Applications

Tested Applications:

IHC, WB,ELISA


Cited Applications:

WB


Species Specificity:

human, pig


Cited Species:

human


Positive WB detected in:

HepG2 cells


Positive IHC detected in:

human thyroid cancer tissue, human lung cancer tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Recommended dilution:

WB : 1:1000-1:8000

IHC : 1:50-1:500

Product Information


Source:

Mouse


Purification method:

Protein A purification


Isotype:

IgG3


Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:

Peptide


Full name:

NK2 homeobox 1


Calculated molecular weight:

42 kDa


Observed molecular weight:

41 kDa


Gene symbol

NKX2-1


Synonyms

BHC, Homeobox protein Nkx 2.1, NK 2, NK2 homeobox 1, NKX2 1, NKX2.1, NKX2-1, NKX2A, TEBP, Thyroid nuclear factor 1, Thyroid transcription factor 1, TITF1, TTF 1, TTF1

Background

Homeobox protein Nkx-2.1 (NKX2-1), also named Thyroid nuclear factor 1,Thyroid transcription factor 1(TTF1). It is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Defects in NKX2-1 are the cause of benign hereditary chorea (BHC), choreoathetosis, hypothyroidism, and neonatal respiratory distress (CHNRD)

Protocols

PRODUCT

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