NapsinA兔单克隆抗体

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NapsinA兔单克隆抗体

NapsinA兔单克隆抗体

human thyroid cancer tissue, human lung cancer tissue
  • 价格¥10106.25
  • 规格1ml
  • 货号HKI0661B
  • 单位
  • 品牌HaoKebio

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HaoKebioHKI0661BNapsinA兔单克隆抗体1ml10106.25

Applications

Tested Applications:

IF, IHC, WB,ELISA


Species Specificity:

human, mouse


Positive WB detected in:

mouse lung tissue


Positive IHC detected in:

human lung cancer tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Positive IF detected in:

PC-3 cells


Recommended dilution:

WB : 1:500-1:1000

IHC : 1:50-1:500

IF : 1:10-1:100

Product Information


Source:

Rabbit


Purification method:

Antigen affinity purification


Isotype:

IgG


Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:

napsin A aspartic peptidase


Calculated molecular weight:

420 aa, 45 kDa


Observed molecular weight:

45-55 kDa


Gene symbol

NAPSA


Synonyms

Asp 4, ASP4, Aspartyl protease 4, KAP, Kdap, NAP1, NAPA, NAPSA, Napsin 1, Napsin A, napsin A aspartic peptidase, Pronapsin A, SNAPA, TA01/TA02

Background

Napsin is found in two isoforms, napsin A and B, with highly homologous nucleotide sequences (91.2%). Napsin A appears to be a functional proteinase, predominantly expressed in lung and kidney. Napsin B is transcribed exclusively in cells related to the immune system and lacks an in-frame stop codon and is believed to be a pseudogene.(PMID:12698189). Napsin A is superior to TTF-1 in distinguishing primary lung ACA from other carcinomas (except kidney), particularly primary lung small cell carcinoma, and primary thyroid carcinoma.(PMID:22288963).

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