IL18兔多克隆抗体

品牌 商品编码 商品名称 规格 单位 单价
HAOKEBIO HK210191L IL18兔多克隆抗体 200ul 2800
HAOKEBIO HK210191S IL18兔多克隆抗体 50ul 1200

Applications

Tested Applications:
IF, IHC, IP, WB, ELISA

Cited Applications:
IF, IHC, WB
Species Specificity:
human

Cited Species:
human, rat

Positive WB detected in:
HeLa cells, A431 cells, HaCaT cells, DU 145 cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:

human tonsillitis tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:500
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
IL-18

Calculated molecular weight:
193 aa, 22 kDa

Observed molecular weight:
22 kDa

Gene symbol
IL18

Synonyms
Iboctadekin, IFN gamma inducing factor, IGIF, IL 1 gamma, IL 18, IL 1g, IL18, IL-18, IL1F4, Interleukin 1 gamma, Interleukin 18, Mature IL18, pre IL18, Pre-IL18

Background

IL18, is a proinflammatory cytokine involved in the development of Th1 cells and in immune response. It can stimulate the NK cells and certain T cells to release IFN gamma which plays an important role in activating the macrophages or other cells. IL18 has been demonstrated to have the potential to enhance Fas ligand-mediated cytotoxicity, which is increased in PE and regulates placental apoptosis. IL18 is synthesized as a 22 kDa precursor and then cleaved into a biologically activate 18 kDa form. This antibody 10663-1-AP is raised against the full length IL18 precursor, and it recognizes both the pre-IL18 and mature IL18 theoretically.

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