杭州浩克生物
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FIS1兔多克隆抗体
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| HAOKEBIO | HK210146L | FIS1兔多克隆抗体 | 200ul | 支 | 2800 |
| HAOKEBIO | HK210146S | FIS1兔多克隆抗体 | 50ul | 支 | 1200 |
|---|
Applications
Applications
Tested Applications:
IF, IHC, IP, WB, ELISA
Cited Applications:
CoIP, IF, IHC, IP, WB
Species Specificity:
human, mouse, rat, pig
Cited Species:
bovine, Chinese hamster ovary (CHO) cell, hamster, human, mouse, pig, rat, squirrel
Positive WB detected in:
HeLa cells, SH-SY5Y cells, pig brain tissue, rat brain tissue, mouse heart tissue, rat heart tissue, mouse brain tissue, Jurkat cells, mouse spleen, rat spleen
Positive IP detected in:
HeLa cells
Positive IHC detected in:
rat brain tissue, human brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected in:
Hepa1-6 cells, HepG2 cells
Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500
IF : 1:50-1:200
Product Information
Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information
Full name:
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
Calculated molecular weight:
17 kDa
Observed molecular weight:
17 kDa
Gene symbol
FIS1
Synonyms
CGI 135, FIS1, FIS1 homolog, hFis1, TPR repeat protein 11, TTC11
Background
Fis1 (fission 1) is an integral mitochondrial outer membrane protein that participates in mitochondrial fission by interacting with dynamin-related protein 1 (Drp1). Excessive mitochondrial fission is associated with the pathology of a number of neurodegenerative or neurodevelopmental diseases. Increased expression of Fis1 has been found in Huntington’s disease (HD)-affected brain, Alzheimer’s disease (AD) patients, and autism spectrum disorder. This antibody was raised against the full-length of human Fis1 protein, and recognizes endogenous Fis1 protein in various lysates. (PMID: 21257639, 21459773, 23333625)
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