ATGL兔多克隆抗体

品牌 商品编码 商品名称 规格 单位 单价
KAOKEBIO HK210028L ATGL兔多克隆抗体 200ul 2800

Applications

Tested Applications:
IP, WB,ELISA

Cited Applications:
IF, IHC, WB
Species Specificity:
human, mouse, rat

Cited Species:
chicken, human, mouse, rat, sheep

Positive WB detected in:
3T3-L1 cells, A431 cells, HeLa cells, human heart tissue, mouse heart tissue, mouse testis tissue, rat heart tissue

Positive IP detected in:
mouse testis tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
patatin-like phospholipase domain containing 2

Calculated molecular weight:
55 kDa

Observed molecular weight:
55 kDa

Gene symbol
PNPLA2

Synonyms
1110001C14Rik, Adipose Triglyceride Lipase, ATGL, DESNUTRIN, FP17548, IPLA2 zeta, PEDF R, PNPLA2, Transport secretion protein 2, TTS 2.2, TTS2, TTS2.2

Background

ATGL, also named as PNPLA2, TTS2 and Desnutrin, catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. It also has acylglycerol transacylase activity. ATGL may act coordinately with LIPE/HLS within the lipolytic cascade. It regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. Defects in ATGL are the cause of neutral lipid storage disease with myopathy (NLSDM). This antibody is specific to ATGL.

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