| 产品名称 | HIF-1α Recombinant antibody |
|---|---|
| 产品编号 | HB50308 |
| Uniprot ID | Q16665 |
| Host Species | Rabbit |
| Reactivity | Human, Mouse |
| Tested Applications | IHC |
| Application | IHC :1:100 -1:200 |
| Background | This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
| Alternative Names | HIF1A, HIF 1α, HIF 1 alpha, Class E basic helix-loop-helix protein 78, Basic-helix-loop-helix-PAS protein MOP1 |
| Immunogen | Synthetic Peptide |
| Subcellular Localization | Nucleus |
| Conjugate | Unconjugated |
| Purification | Affinity Purification |
| Formulation | Liquid |
| Storage | Store at -20°C |
| Figure ID 1 | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%. |
| Figure ID 2 | HB50308 |
| 保质期 | 12 months |
