| 产品名称 | 4E BP1 Recombinant antibody |
|---|---|
| 产品编号 | HB10013 |
| Uniprot ID | Q13541 |
| Host Species | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Tested Applications | WB, IHC-P, ICC/IF, FC, IP |
| Application | WB: 1:1000 IHC-P: 1:100-1:200 ICC/IF: 1:200-1:500 FC: 1:20-1:50 IP: 1:20 |
| Background | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008] |
| Alternative Names | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008] |
| Immunogen | A synthetic peptide of human eIF4EBP1 |
| Calculated MW | 13 kDa |
| Observed mw | 15-20 kDa |
| Subcellular Localization | nucleus, cytoplasm |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Purification | Affinity Purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Formulation | Liquid |
| Storage | Store at -20°C |
| 曾用货号 | B35009D |
| 保质期 | 12 months |
