MyelinBasicProtein兔单克隆抗体

品牌 商品编码 商品名称 规格 单位 单价
HAOKEBIO HKI0731B MyelinBasicProtein兔单克隆抗体 1ml 11812.5

Applications

Tested Applications:

IHC, WB, ELISA


Cited Applications:
IF, IHC, WB

Species Specificity:
human, mouse, rat

Cited Species:
human, mouse, rat

Positive WB detected in:
mouse brain tissue, rat brain tissue

Positive IHC detected in:

mouse brain tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Recommended dilution:
WB : 1:2000-1:16000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
myelin basic protein

Calculated molecular weight:
33 kDa

Observed molecular weight:
17-22 kDa

Gene symbol
MBP

Synonyms
MBP, Myelin A1 protein, Myelin basic protein

Background

MBP belongs to the myelin basic protein family. The classic group of MBP isoforms (isoform 4-isoform 14) are the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. MBP has six isoforms. Catalog#10458-1-AP is capable of recognizing multiple isoforms of MBP.

Protocols

PRODUCT SPECIFIC PROTOCOLS

WB proto

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