FactorVIII受体兔单克隆抗体

品牌 商品编码 商品名称 规格 单位 单价
HAOKEBIO HKI0681B FactorVIII受体兔单克隆抗体 1ml 11812.5

Applications

Tested Applications:
WB,ELISA

Species Specificity:
Human

Positive WB detected in:
human plasma tissue, human blood tissue

Recommended dilution:
WB : 1:1000-1:8000

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
coagulation factor VIII, procoagulant component

Calculated molecular weight:
2351 aa, 267 kDa

Observed molecular weight:
70 kDa

Gene symbol
F8

Synonyms
AHF, Antihemophilic factor, Coagulation factor VIII, DXS1253E, F8, F8B, F8C, FVIII, HEMA, Procoagulant component

Background

F8, also named as AHF and F8C, belongs to the multicopper oxidase family. F8, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa. F8 can be cleaved to 4 chains: F8a heavy chain, 200 kDa isoform, F8a heavy chain, 92 kDa isoform, F8 B chain and F8a light chain. This antibody can recognize the light chain.

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