杭州浩克生物
p40兔单克隆抗体
12品牌 商品编码 商品名称 规格 单位 单价 HAOKEBIO HKI0171A p40兔单克隆抗体 100ul 支 2250 Applications Tested Applications: IF, IHC, WB,ELISA Species Sp...
查看全文COX-2兔单克隆抗体
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| HAOKEBIO | HKI0591B | COX-2兔单克隆抗体 | 1ml | 支 | 5512.5 |
Applications
Tested Applications:
IF, IHC, WB, ELISA
Cited Applications:
IF, IHC, WB
Species Specificity:
human, mouse
Cited Species:
human, mouse, rat
Positive WB detected in:
A549 cells, mouse lung tissue
Positive IHC detected in:
human lung tissue, human spleen tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected in:
mouse lung tissue
Recommended dilution:
WB : 1:500-1:1000
IHC : 1:100-1:400
IF : 1:50-1:500
Product Information
Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information
Full name:
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Calculated molecular weight:
604 aa, 68 kDa
Observed molecular weight:
69 kDa
Gene symbol
PTGS2
Synonyms
COX 2, COX2, COX2/ Cyclooxygenase 2, COX2/ Cyclooxygenase 2/ PTGS2, Cyclooxygenase 2, GRIPGHS, hCox 2, PGG/HS, PGH synthase 2, PGHS 2, PHS 2, PHS II, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, PTGS2
Background
COX2 (Prostaglandin G/H synthase 2, PTGS2) mediates the formation of prostaglandins from arachidonate. Its subunit structure is homodimer. The fully N-glycosylated PTGS2 is 72-74 kDa and the aglycosylated is 66 kDa(PMID:19656660 ). It also expresses a band of 39 kDa after unspecific cleavage(PMID:17509125 ). The 50 kDa band of fragmented PTGS2 has also previously been detected in AD brains(PMID:14724276 ).
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