P53兔多克隆抗体

品牌 商品编码 商品名称 规格 单位 单价
HAOKEBIO HK210262L P53兔多克隆抗体 200ul 2800
HAOKEBIO HK210262M P53兔多克隆抗体 100ul 1960
HAOKEBIO HK210262S P53兔多克隆抗体 50ul 1200

Applications

Tested Applications:
IF, IP, WB, ELISA

Cited Applications:
ChIP, CoIP, IF, IP, WB
Species Specificity:
human, rat, mouse

Cited Species:
Artemia sinica, goat, human, pig, rat, sheep

Positive WB detected in:
SMMC-7721 cells, HEK-293 cells, MCF-7 cells, rat colon tissue, mouse spleen tissue, A431 cells, mouse colon tissue

Positive IP detected in:
A431 cells

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:1000-1:6000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
tumor protein p53

Calculated molecular weight:
44 kDa

Observed molecular weight:
53 kDa

Gene symbol
TP53

Synonyms
Antigen NY CO 13, Cellular tumor antigen p53, LFS1, P53, Phosphoprotein p53, TP53, TRP53, tumor protein p53, Tumor suppressor p53

Background

TP53, also known as P53 and NY-CO-13, belongs to the p53 family and has 9 isoforms. In SDS-Page, the observed molecular weight is about 53 kDa. TP53 acts as a tumor suppressor in many tumor types, including growth arrest or apoptosis depending on the physiological circumstances and cell types. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. TP53 Localizes in the nucleus in most cells but found in the cytoplasm in some cells. (PMID: 26166714; PMID: 25225161)

Protocols

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