杭州浩克生物
Calponin兔单克隆抗体
6品牌 商品编码 商品名称 规格 单位 单价 HAOKEBIO HKI0711A Calponin兔单克隆抗体 100ul 支 938 Applications Tested Applications: IHC, WB,ELISA Cited Applicatio...
详情咨询p38抗体
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| HAOKEBIO | HK14064M | p38抗体 | 100ul | 支 | 1960 |
Applications
Tested Applications:
IF, IHC, WB, ELISA
Cited Applications:
IF, IHC, WB
Species Specificity:
human, mouse, rat
Cited Species:
Artemisia sphaerocephala Krasch, CHICKEN, fish, human, mouse, pig, rabbit, rat
Positive WB detected in:
HeLa cells, Jurkat cells, mouse heart tissue, rat heart tissue
Positive IHC detected in:
human colon cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected in:
HepG2 cells
Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500
IF : 1:20-1:200
Product Information
Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information
Full name:
mitogen-activated protein kinase 14
Calculated molecular weight:
360 aa, 41 kDa
Observed molecular weight:
35 kDa, 41 kDa
Gene symbol
MAPK14
Synonyms
CSAID binding protein, CSBP, CSBP1, CSBP2, CSPB1, EXIP, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, MAPK 14, MAPK14, MAX interacting protein 2, Mxi2, p38, p38ALPHA, PRKM14, PRKM15, RK, SAPK2A
Background
MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has some isoforms with MW 29-31 kDa, 35 kDa and 41 kDa.
Protocols
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