p38抗体

品牌 商品编码 商品名称 规格 单位 单价
HAOKEBIO HK14064M p38抗体 100ul 1960

Applications

Tested Applications:
IF, IHC, WB, ELISA

Cited Applications:
IF, IHC, WB
Species Specificity:
human, mouse, rat

Cited Species:
Artemisia sphaerocephala Krasch, CHICKEN, fish, human, mouse, pig, rabbit, rat

Positive WB detected in:
HeLa cells, Jurkat cells, mouse heart tissue, rat heart tissue

Positive IHC detected in:

human colon cancer tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
mitogen-activated protein kinase 14

Calculated molecular weight:
360 aa, 41 kDa

Observed molecular weight:
35 kDa, 41 kDa

Gene symbol
MAPK14

Synonyms
CSAID binding protein, CSBP, CSBP1, CSBP2, CSPB1, EXIP, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, MAPK 14, MAPK14, MAX interacting protein 2, Mxi2, p38, p38ALPHA, PRKM14, PRKM15, RK, SAPK2A

Background

MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has some isoforms with MW 29-31 kDa, 35 kDa and 41 kDa.

Protocols

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