CEA兔单克隆抗体

品牌 商品编码 商品名称 规格 单位 单价
HAOKEBIO HKI0601A CEA兔单克隆抗体 100ul 1088

Applications

Tested Applications:
IHC,ELISA

Cited Applications:
chIP, IHC, WB

Species Specificity:
human

Cited Species:
human

Positive IHC detected in:

human colon cancer tissue, human appendicitis tissue, human stomach cancer tissue, human lung cancer tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Recommended dilution:
IHC : 1:200-1:800

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
carcinoembryonic antigen-related cell adhesion molecule 5

Calculated molecular weight:
77 kDa

Observed molecular weight:
Gene symbol
CEACAM5

Synonyms
Carcinoembryonic antigen, CD66e, CEA, CEACAM5, Meconium antigen 100

Background

Carcinoembryonic antigen (CEA), also known as CEACAM5 or CD66e, is a cell surface glycoprotein belonging to the immunoglobulin superfamily, mainly serving as a cell adhesion molecule mediating intercellular contact by both homophilic and heterophilic binding (PMID: 21731662). CEA inhibits anoikis and plays a role in tumorigenesis and metastasis. CEA has been found to be overexpressed in a wide variety of human cancers, including colon, breast, and lung (PMID: 17167768). CEA is a tumor marker and is routinely exploited for diagnosis.

Protocols

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