杭州浩克生物
CD19兔单克隆抗体
1品牌 商品编码 商品名称 规格 单位 单价 HAOKEBIO HKI0451A CD19兔单克隆抗体 100ul 支 1125 Applications Tested Applications: FC, IHC, WB,ELISA Cited Applicati...
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| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| HAOKEBIO | HKI0351A | CD31兔单克隆抗体 | 100ul | 支 | 1313 |
Applications
Tested Applications:
IF, IHC, WB, ELISA
Cited Applications:
IF, IHC, WB
Species Specificity:
Human
Cited Species:
human
Positive WB detected in:
human peripheral blood platelets, Jurkat cells, THP-1 cells
Positive IHC detected in:
human liver cancer tissue, human breast cancer tissue, human tonsillitis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected in:
human liver cancer tissue
Recommended dilution:
WB : 1:5000-1:50000
IHC : 1:5000-1:20000
IF : 1:200-1:800
Product Information
Source:
Mouse
Purification method:
Protein A purification
Isotype:
IgG1
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Aliquoting is unnecessary for -20oC storage.
Full name:
platelet/endothelial cell adhesion molecule
Calculated molecular weight:
83 kDa
Observed molecular weight:
120-130 kDa
Gene symbol
PECAM1
Synonyms
CD31, EndoCAM, FLJ58394, GPIIA, PECA1, PECAM 1, PECAM1, VEC marker
Background
Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489)
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