杭州浩克生物
ARMET兔多克隆抗体
3品牌 商品编码 商品名称 规格 单位 单价 KAOKEBIO HK210018L ARMET兔多克隆抗体 200ul 支 2800 Applications ested Applications: IHC, WB,ELISA Species Specificit...
详情咨询p40兔单克隆抗体
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| HAOKEBIO | HKI0171A | p40兔单克隆抗体 | 100ul | 支 | 2250 |
Applications
Tested Applications:
IF, IHC, WB,ELISA
Species Specificity:
Human, mouse, rat
Positive WB detected in:
Jurkat cells, HeLa cells, HEK-293 cells, HSCT6 cells, RAW 264.7 cells
Positive IHC detected in:
human lung cancer tissue, human colon tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected in:
A549 cells
Recommended dilution:
WB : 1:1000-1:6000
IHC : 1:500-1:2000
IF : 1:50-1:500
Product Information
Source:
Mouse
Purification method:
Protein A purification
Isotype:
IgG1
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information
Full name:
Rab9 effector protein with kelch motifs
Calculated molecular weight:
41 kDa
Observed molecular weight:
40 kDa
Gene symbol
RABEPK
Synonyms
40 kDa Rab9 effector protein, p40, RAB9P40, RABEPK
Background
Rab9 GTPase is required for the transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network in living cells, and in an in vitro system that reconstitutes this process. P40 is an effector of Rab9 that interacts preferentially with the active form of Rab9. p40 does not interact with Rab7 or K-Ras; it also fails to bind Rab9 when it is bound to GDI. The protein is found in cytosol, yet a significant fraction (~30%) is associated with cellular membranes. P40 is a very potent transport factor in that the pure, recombinant protein can stimulate, significantly, an in vitro transport assay that measures transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network
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