杭州浩克生物
BAX兔多克隆抗体
3品牌 商品编码 商品名称 规格 单位 单价 KAOKEBIO HK210032L BAX兔多克隆抗体 200ul 支 2800 KAOKEBIO HK210032M BAX兔多克隆抗体 100ul 支 1960 Applications Tested Ap...
详情咨询p70(S6K)鼠单克隆抗体
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| HAOKEBIO | HK510141L | p70(S6K)鼠单克隆抗体 | 200ul | 支 | 2800 |
Applications
Tested Applications:
IHC, WB,ELISA
Cited Applications:
WB
Species Specificity:
Human, Mouse, Rat
Cited Species:
human, mouse
Positive WB detected in:
Jurkat cells, HEK-293 cells, HSC-T6 cells, NIH/3T3 cells
Positive IHC detected in:
human lung cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Recommended dilution:
WB : 1:1000-1:6000
IHC : 1:200-1:800
Product Information
Source:
Mouse
Purification method:
Protein G purification
Isotype:
IgG1
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information
Full name:
ribosomal protein S6 kinase, 70kDa, polypeptide 1
Calculated molecular weight:
59 kDa
Observed molecular weight:
51-59 kDa
Gene symbol
RPS6KB1
Synonyms
p70 alpha, p70 ribosomal S6 kinase alpha, p70 S6 kinase alpha, p70 S6K, p70 S6K 1, p70 S6K alpha, p70 S6KA, p70(S6K), p70(S6K) alpha, p70S6K, P70S6K1, PS6K, Ribosomal protein S6 kinase I, RPS6KB1, S6K, S6K beta 1, S6K1, STK14A
Background
RPS6KB1(Ribosomal protein S6 kinase beta-1) is also named as STK14A, p70 S6KA and belongs to the S6 kinase subfamily. RPS6KB1 is a major substrate of MTOR and acts as a crucial effector of MTOR signaling pathway. It plays a key role in cell growth and proliferation by regulating INS sensitivity, metabolism, protein synthesis, and cell cycle. RPS6KB1 may play an important role in the progression of HCC and could serve as a potential molecular target for HCC therapy (PMID:22684641). RPS6KB1 is a 70 kDa protein and has 5 isoforms with the calculated molecular mass of 51-59kDa produced by alternative initiation.
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