IL-4鼠单克隆抗体

品牌 商品编码 商品名称 规格 单位 单价
HAOKEBIO HK510115M IL-4鼠单克隆抗体 100ul 1960

Applications

Tested Applications:
IF, IHC, WB, ELISA

Cited Applications:
ELISA, IF, IHC, WB
Species Specificity:
human, pig

Cited Species:
human, rat

Positive WB detected in:
Jurkat cells

Positive IHC detected in:

human tonsillitis tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Positive IF detected in:
human breast cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:200-1:800

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
interleukin 4

Calculated molecular weight:
153 aa, 17 kDa

Observed molecular weight:
18 kDa

Gene symbol
IL4

Synonyms
B cell stimulatory factor 1, Binetrakin, BSF 1, BSF1, IL 4, IL4, IL-4, interleukin 4, PS1TP5BP1

Background

IL4 is a cytokine produced by CD4+ T cells in response to helminthes and other extracellular parasites. It promotes the proliferation and differentiation of antigen presenting cells. IL4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival.

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